Tuesday 25 March 2014

26 March, 2014

25 cancer centres coming to India
Kolkata: To improve access to healthcare facilities for the rising number of cancer patients in India, 25 world-class private cancer care centres would be set up across the country at an investment of Rs 720 crore.
GE Healthcare, a unit of General Electric Company, today announced a strategic partnership with Cancer Treatment Services International (CTSI) to develop these cancer care centres which will offer latest technology for diagnosing and treating cancer.
"We believe a partnership like this one presents a great opportunity to confront India's cancer challenge head on," John Dineen, president and CEO of GE Healthcare, said in a statement here.
The new centres will follow the same standards of care found at the world's top cancer hospitals delivered at affordable price points, it said.
The network will be built at an investment of Rs 720 crore over a period of five years.
The incidence of cancer is sharply rising in India with a prevalence of 3 million cases and an addition of 1.23 million new cases being reported every year.
The mortality rates are very high due to late detection, access and affordability to care. Estimates suggest every two minutes three patients succumb to this deadly and costly disease.
CTSI president and CEO Joe Nicholas said they have built a proven healthcare delivery model tailored to making the highest quality cancer care accessible and affordable.
They aim to elevate the access, affordability and standard of cancer care in India.
GE and CTSI will configure the network in a hub-and-spoke fashion, with all the centers linked by a sophisticated IT network to a hub and supported by a multi-national group of clinicians, and administrators.
The hub will be a centre of excellence with full diagnostic imaging and treatment capabilities while the spoke will have the ability to deliver a range of screening, staging and treatment options, the statement said.
The first hub center, American Oncology Institute, CTSI's international brand, is already operational in Hyderabad while the first spoke or remote centre is being set up in Andhra Pradesh. 
26.03.2014



An antibiotic that can be switched on and off with light!
London: In a breakthrough, scientists have produced an antibiotic whose biological activity can be controlled with light - opening up new options in treating bacterial infections as side effects can be minimised by switching.
Thanks to the robust diarylethene photoswitch, the anti-microbial effect of the peptide mimetic can be applied in a spatially and temporally specific manner.
Photoswitchable molecules modify their structure and properties when exposed to light of an adequate wavelength.
Among the photoswitches known are diarylethenes.
By reversible photoisomerization - a reversible light-induced internal relocation of the molecule - the open form is turned into a closed (inactivated) form.
Professor Anne S. Ulrich from Karlsruhe Institute of Technology (KIT) in Germany, along with researchers from University of Kiev, produced a photoswitchable peptide mimetic based on a diarylethene scaffold that can be photoisomerised reversibly.
The team then treated a bacterial film with the inactivated antibiotic and exposed it to light via a mask.
As a result, the photoswitchable diarylethene was converted from a closed into an open form.
Due to the structural modification induced, the entire substance molecule had a much higher anti-microbial effect.
“In the future, such photoactivable antibiotics might be used as smart therapeutic agents against local bacterial infections,” Ulrich explained.
Based on this strategy, new peptide-based agents against cancer might be feasible as the newly developed photoactivable building block can also be applied in other peptide sequences.
The research was published in the journal Angewandte Chemie.
26.03.2014








The best way to find yourself is to lose yourself in the service of others


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