Thursday, 30 October 2014

31, October 2014

UV-activated membrane may replace injections for premature babies

According to a study appeared in the journal Advanced Functional Materials, drugs can be delivered to premature babies via a plaster rather than an injection. Instead of using injections or probes, it will in future be possible to deliver drugs to premature babies via a plaster. Researchers have developed a UV-activated membrane, which releases a gentle dose of medication to the skin of a patient. The plaster, which delivers drug through the membrane, can be simply stuck to the skin of the premature baby, after which it will provide the tiny patient with a continuous dose of, say, caffeine for several hours, without stressing the child as an injection would have done.

For some years now premature babies have been given caffeine to prevent respiratory arrest. The membrane developed at the Swiss Federal Laboratories for Materials Science and Technology changes its properties when it is irradiated with ultraviolet (UV) light. ‘A similar effect is seen in photochromatic sunglasses, where silver-doped glass reacts to UV light by darkening,’ the researchers noted. ‘In the new medicinal membranes, however, another light-sensitive chemical group, called spiropyrans, is active,’ they added.  

When activated, these make the membrane more permeable, so that the drug is able to pass through it more rapidly, a capability which is retained for several hours. In the absence of UV irradiation, the membrane simply prevents the active agent from permeating through it.


31.10.2014



Living in urban area doesn’t improve health outcomes in people with heart disease

A study published in the journal Circulation: Cardiovascular Quality and Outcomes suggested that people living in rural areas are at an equal risk of dying due to heart disease as their urban counterparts, unlike suggested by earlier research that health outcomes are different for those living in rural and urban areas.

The study, carried out by researchers at Women’s College Hospital in Ontario and the Institute for Clinical Evaluative Sciences (ICES) and led by an Indian-origin scientist, shows that regardless of the fact that people in rural areas don’t have proper access to health care they are not at an increased risk of dying due to heart disease compared to those living in urban areas who have all the facilities.

This the first ever study examining outpatient quality of care between urban and rural communities. The study analysed records of more than 38,000 people with chronic ischemic heart disease living in either urban or rural areas. According to the analysis, people living in rural areas had lesser specialist visits but visited hospital emergency departments more frequently for care. They were prescribed statins less often, were tested less frequently for cholesterol and blood sugar levels but experienced a similar risk of hospitalisation and death compared to urban counterparts.

These observations contradicts all existing research that suggested gaps in care for those living in rural areas and urban areas. ‘Research has long suggested people with heart disease in rural areas are at a disadvantage when it comes to access to health care and longevity,’ said Dr Sacha Bhatia, lead author of the study and a cardiologist at Women’s College Hospital. ‘Our study shows once a patient leaves the hospital their overall health outcomes are similar regardless of where they live,’ said Bhatia.

The researchers said while those living in rural areas access their care differently, it did not result in poor health outcomes. ‘From our study, we know that people with heart disease in rural areas tend to rely heavily on emergency departments for their care because of a lack of outpatient access to family doctors and specialists,’ said Bhatia.  



31.10.2014














Watch your thoughts, they become words; watch your words, they become actions; watch your actions, they become habits; watch your habits, they become character; watch your character, it becomes your destiny




          Lao Tzu


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