Sunday 10 April 2016

11 April, 2016

Common painkiller may hamper our ability to notice errors

 A common and effective painkiller, acetaminophen, may impede the brain's ability to detect errors, scientist have found for the first time.
The research from the University of Toronto and University of British Columbia in Canada is the first neurological study to look at how acetaminophen could be inhibiting the brain response associated with making errors. For the study, two groups of 30 participants were given a target-detection task called the Go or No Go.
Participants were asked to hit a Go button every time the letter F flashed on a screen but refrain from hitting the button if an E flashed on the screen. "The trick is you're supposed to move very quickly capturing all the GOs, but hold back when you see a No Go," said Randles.
Electroencephalogram (EEG) was used to measure electrical activity in the brain of the participants. The researchers were looking for a particular wave called Error Related Negativity (ERN) and Error Related Positivity (Pe).
Essentially what happens is that when people are hooked up to an EEG and make an error in the task there is a robust increase in ERN and Pe.
One group, which was given 1,000 milligrammes of acetaminophen - the equivalent of a normal maximum dose - showed a smaller Pe when making mistakes than those who did not receive a dose, suggesting that acetaminophen inhibits our conscious awareness of the error.
"It looks like acetaminophen makes it harder to recognise an error, which may have implications for cognitive control in daily life," said Randles. Cognitive control is an important neurological function because people are constantly doing cognitive tasks that flow automatically like reading, walking or talking. These tasks require very little cognitive control because they are well mapped out neurological processes, said Randles.
"The task we designed is meant to capture that since most of the stimuli were Go, so you end up getting into a routine of automatically hitting the Go button," he said. "When you see a No Go, that requires cognitive control because you need to interrupt the process," he said.
The research was published in the journal Social Cognitive and Affective Neuroscience.  
11.04.2016








A failure establishes only this that our determination to succeed was not strong enough


Christian Nestell Bovee

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