Thursday, 11 April 2013

12 April, 2013


Father of IVF Robert Edwards passes away
British scientist Robert Edwards, known as ‘father’ of world’s first test-tube baby breathed his last on Wednesday, the Cambridge University announced. The 87-year-old died following prolonged illness. Edwards, who was awarded Nobel Prize for his pioneering work in developing in vitro fertilisation (IVF) along with his colleague Patrick Steptoe, led to the birth of the first ‘test-tube baby’ Louise Brown in 1978, Xinhua reported.
The invention made millions of childless couples’ dream come true worldwide, as figures show about four million babies have been born with the help of IVF treatment. In India, IVF was popularised last year thanks to Aamir Khan and Kiran Rao opting for the procedure and publicly admitting it.
‘It is with deep sadness the family announces that Professor Sir Robert Edwards, Nobel prize winner, scientist and co-pioneer of IVF, passed away peacefully in his sleep April 10, 2013 after a long illness,’ a statement from Cambridge university said.
Born in Yorkshire in northern England Sep 27, 1925, into a working-class family, Edwards served in the British army during World War II before returning home to study first agricultural sciences and then animal genetics. Building on earlier research which showed that egg cells from rabbits could be fertilised in test tubes when sperm was added, Edwards developed the same technique for humans.
In a laboratory in Cambridge, eastern England, in 1968, he first saw life created outside the womb in the form of a human blastocyst, an embryo that has developed for five to six days after fertilisation. He was made a Fellow of the Royal Society, Britain’s foremost science institution, in 1984. He was also appointed an emeritus professor at Cambridge in 1989.
12.04.2013


This gen adults less healthy than previous

Despite their greater life expectancy, the adults of today are less "metabolically" healthy than their counterparts of previous generations, according to a new study from the Netherlands.
Assessing the trends, the investigators concluded that "the more recently born generations are doing worse", and warn "that the prevalence of metabolic risk factors and the lifelong exposure to them have increased and probably will continue to increase".

The study analysed data on more than 6,000 individuals in the Doetinchem Cohort Study, which began in 1987 with follow-up examinations after six, 11, and 16 years.(1,2) The principal risk factors measured were body weight, blood pressure, total cholesterol levels (for hypercholesterolaemia) and levels of high-density lipoprotein (HDL) cholesterol, which is considered "protective".

The subjects were stratified by sex and generation at baseline into ten-year age groups (20, 30, 40, and 50 years); the follow-up analyses aimed to determine whether one generation had a different risk profile from a generation born ten
years earlier - what the investigators called a "generation shift".

Results showed that the prevalence of overweight, obesity, and hypertension increased with age in all generations, but in general the more recently born generations had a higher prevalence of these risk factors than generations born ten years earlier.

For example, 40 per cent of the males who were in their 30s at baseline were classified as overweight; 11 years later the prevalence of overweight among the second generation of men in their 30s had increased to 52 per cent (a statistically significant generational shift). In
women these unfavourable changes in weight were only evident between the most recently born generations, in which the prevalence of obesity doubled in just 10 years.

The study was recently presented in the European Journal of Preventive Cardiology.
12.04.2013





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