Sunday, 25 November 2012

26 November, 2012 Clippings


Reading and writing keeps ageing brains healthy!
A new study says that reading and writing can preserve brains of older people and insure them against deterioration as they age.
Konstantinos Arfanakis and colleagues from Rush University Medical Centre and Illinois Institute of Technology, Chicago, examined the effect of late-life cognitive activity on the brain’s white matter, composed of nerve fibres, or axons, that transmit information through the brain. Previous research, unlike that of Arfanakis, had linked late-life cognitive activity with better mental sharpness, according to a statement from Rush University and Illinois Institute.
‘Reading the newspaper, writing letters, visiting a library, attending a play or playing games, such chess or checkers, are all simple activities that can contribute to a healthier brain,’ Arfanakis said.
The researchers used a magnetic resonance imaging (MRI) method known as DTI to generate data on diffusion anisotropy, a measure of how water molecules move through the brain. These values in white matter drop with aging, injury and disease.
The study included 152 elderly participants with an average age of 81 years, from the Rush Memory and Aging Project, a large-scale study looking at risk factors for Alzheimer’s disease. They were without dementia or mild cognitive impairment, based on a detailed clinical evaluation. Researchers asked them to rate on a scale of one to 5 the frequency with which they participated in a list of mentally engaging activities during last year, such as reading newspapers and magazines, writing letters and playing cards and board games.
Data analysis revealed significant associations between the frequency of cognitive activity in later life and higher water molecule diffusion in the brain.
These findings were presented at the annual meeting of the Radiological Society of North America (RSNA) in Chicago in the US.
26.11.2012
Drug that sends cancers 'to sleep' brings hope for millions
Scientists have discovered how to send cancer cells “to sleep” to stop the disease in its tracks.
They have created a new drug that “flips” molecular switches in the cancer’s structure so it cannot multiply, the Daily Express reported.
The drug, called Aflibercept, which is administered as a 30-minute infusion alongside chemotherapy, uses a novel mechanism that effectively fools tumours into becoming dormant.
Trials involving 1,406 patients have shown the breakthrough could prolong life by two years in some patients with advanced bowel cancer who have already undergone chemotherapy.
Aflibercept had a “statistically significant survival benefit” compared to conventional drug regimes treating bowel cancer, the researchers said.
Dr Rob Glynne Jones, Macmillan Clinical Lead for Gastrointestinal Cancer at Mount Vernon Hospital in Northwood, Middlesex, said: “The trial results were positive."
“Around 10,000 patients a year die from bowel cancer and most of them are having some form of chemotherapy so it is theoretically applicable to those. I am sure this drug will have a research programme and they will be extending it to all other cancers. Maybe they will find other cancers where it may be more effective,” he added.
The study has been published in the Journal of Clinical Oncology.
26.11.2012






Choose the life that is most useful, and habit will make it the most agreeable

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