Sunday, 2 November 2025

IT professional ignored borderline cholesterol at 25, had heart attack at 35: How you shouldn’t ignore even mild spike in LDL

 

Source: https://indianexpress.com/article/health-wellness

At 25, Aadya Waadiyar (name changed) had to undergo a pre-employment medical screening before she could settle into her new IT job. Her numbers were borderline high, her total cholesterol being 220 mg/dL, (the normal being less than 200 mg/dL). Total cholesterol is a sum of low-density lipoprotein (LDL) or bad cholesterol, high-density lipoprotein (HDL) or good cholesterol and triglycerides or blood fats from excess calories. “I didn’t know anything about why their single scores also mattered. Or why I couldn’t roll back the readings with a few extra runs. At 25, you are young and you think these slightly elevated figures won’t make much of a difference. Except it did, when I had a heart attack at 35, exactly a decade later,” she says.

“People can have high cholesterol for years, decades even and not experience any discomfort till it piles up as plaque in the heart vessels, blocks the blood flow and triggers a heart attack,” says Dr Ranjan Shetty, lead cardiologist and medical director at Sparsh Hospital, Bengaluru, who did an angioplasty (a medical procedure to open blocked arteries). “She was a fit person and had no other risk factor. So I asked her about her family history. Then she told me that her father had had a heart attack, that too at age 50. And suddenly everything became clear,” he adds.

When you have a family history of young heart attacks, it means you can inherit genes that lead to high cholesterol, high blood pressure, or other risk factors for heart disease. “Some patients have familial hypercholesterolemia, a hereditary disorder where your body can’t effectively remove LDL cholesterol from your blood, leading to its build-up in the bloodstream,” says Dr Shetty. “Aadya had a total cholesterol of 220 mg/dL at 25. Though she didn’t know it then, that figure in her early 20s was actually very indicative. Anything above 180 mg/dL in your early 20s usually means you have a family history of risk factors. It is a red flag to do follow-up tests and monitor your condition regularly to prevent a heart attack,” he adds.

Why cholesterol management needs to begin early

Cholesterol takes a long time to get to dangerous levels in the body. “Plaque formation typically begins from a person’s childhood. Then it takes a long time, usually a decade and actually gives you time to rectify yourself with lifestyle correction. Once it reaches high levels, then you would need medication to bring it down,” says Dr Shetty. “I wish I had known basic facts about cholesterol and my family history. Then perhaps I could have prevented my heart attack,” says Aadya.

When should young people do a cholesterol test?

Adolescents, says Dr Shetty, should have their cholesterol checked between ages 18 and 21. Children who have obesity or diabetes may need to be screened earlier and monitored more frequently. Those with family history and co-morbidities should go for annual check-ups. Those with normal readings and without co-morbidities should go for their next test within a four to six-year window.

What do the numbers in a cholesterol test mean?

“Since Indians are more prone to heart attacks a decade earlier than other populations and 31 per cent of them have high LDL (bad) cholesterol, while being genetically predisposed to low HDL (good) cholesterol, the checks and balances ought to be calibrated very well,” says Dr Shetty. So LDL, according to him, should ideally be under 70 mg/dL while the minimum HDL should be no less than 40 mg/dL. Triglycerides should be less than 150 mg/dL. Simultaneously, check and balance other components of heart health, like blood sugar and blood pressure.

Dr Shetty focusses on LDL and triglyceride levels to assess risk. “The two together are a potent combination. One must also measure lipoprotein-A or Lp(a), which carries cholesterol in the blood. About 25 per cent Indians have high levels, which should ideally be lower than 30 mg/dL. That’s why it should be tested at least once to eliminate risk factors,” he says.

What to do for preventive heart health?

Looking back, Aadya realises that long hours of sedentary work had limited her physical activity while work stress had fuelled her desire for convenience foods. “I didn’t realise that I was piling up new risk factors with diet and low exercise,” says the IT professional, who now has low-fat, low calorie food. She has more fruit and vegetable salads as the soluble fibres in them bind to the cholesterol in the digestive system and remove it from the body. She gets her Omega 3 fatty acids from almonds, walnuts and flaxseeds.

Dr Shetty has advised her strength training and she does them at least twice a week, doing five-minute squats and lunges at her workplace. Her cholesterol is now within range.

 

Monday, 25 August 2025

Why blood sugar readings may look confusing: Patient had slightly high fasting blood glucose of 107 mg/dL but HbA1c was too high, above 7%

 

Source: https://indianexpress.com/article/health-wellness

Blood glucose tests are important tools to understand how well your body is managing glucose. Sometimes, though, the results can be confusing. For example, a patient showed me he had a fasting blood glucose of 107 mg/dL (which looks only slightly above normal), but the HbA1c (average blood sugar count of three months) was above 7 per cent (which is clearly in the diabetic range, the normal being 5.7 per cent). How can this happen and what does it mean? Let’s break it down in simple terms.

Fasting Blood Glucose (FBS): This test measures your blood glucose at a single point in time, after you have not eaten for at least eight hours.

Normal: less than 100 mg/dL

Prediabetes: 100–125 mg/dL

Diabetes: 126 mg/dL or higher

So, a fasting glucose of 107 mg/dL means the person is in the prediabetes range.

HbA1c (Glycated Hemoglobin): This test reflects your average blood glucose over the past two to three months. It shows how much glucose has been sticking to your red blood cells.

Normal: less than 5.7%
Prediabetes: 5.7–6.4%
Diabetes: 6.5% or higher

An HbA1c of over 7 per cent indicates sub-optimally controlled diabetes, with average blood glucose around 170–180 mg/dL.

Why do the results differ?

This mismatch happens more often than you might think. Remember that blood glucose rises after meals or what we call post-prandial spikes. Fasting glucose may look almost normal but after eating, the person’s glucose may rise very high. These repeated spikes raise the HbA1c, even though fasting numbers look okay.

Fasting glucose is just one snapshot and may reflect recent improvement in glucose levels. HbA1c shows the bigger picture over months and will be influenced by the glucose pattern of the last three months. Some people first develop high glucose after meals (postprandial hyperglycemia) before fasting glucose goes up.

Rarely, conditions like anemia, thalassemia, kidney disease or certain medications can affect HbA1c readings.

What does this mean for the patient?

The HbA1c reading of over 7 per cent cannot be ignored. It means that overall blood glucose has been consistently high, even if the fasting reading looks only mildly elevated. This person does have diabetes and needs lifestyle changes and possibly medication. Fasting glucose of 107 mg/dL may give a false sense of security, but HbA1c is more reliable for long-term risk.

Why is this important?

Uncontrolled blood glucose, reflected in a high HbA1c, increases the risk of heart disease and stroke, kidney damage, nerve problems (neuropathy), eye damage (retinopathy) and slows down wound healing. Early diagnosis and management can prevent these complications.

What should be done?

Sometimes doctors repeat the tests or add an Oral Glucose Tolerance Test (OGTT) to be sure. Review your lifestyle. Eat a balanced diet with less glucose and refined carbs. Exercise at least 30 minutes a day, five days a week. Maintain a healthy weight. If lifestyle changes alone don’t help, doctors may prescribe medicines like metformin or others depending on the case. Keep checking blood glucose and HbA1c to track progress. Fasting tests can sometimes miss the bigger picture but HbA1c reveals how glucose behaves over months.

 

Sunday, 8 June 2025

Blood sugar double risk you didn’t know about: How black coffee and no sleep can push up levels

 Source: https://indianexpress.com/article/health-wellness

Getting less than six hours of sleep regularly can interfere with your body’s ability to regulate blood sugar.

A young patient of mine reported that her blood sugar levels were not quite in range despite keeping herself active and eating clean. We had suggested lifestyle correction as the first step to control her body weight but she said her regular exercises were tiring her out. Meanwhile her blood sugar levels showed an uptick. What was going wrong?

Then I asked her if she was sleeping enough. “Honestly, I sleep about five hours a night, sometimes less. I have a lot of daily deadlines to meet, so I rely on coffee — maybe five or six cups a day — to stay alert,” she told me. There lay my answer. Poor sleep and caffeine are bad news for blood sugar.

Sleep and blood sugar spikes

Getting less than six hours of sleep regularly can interfere with your body’s ability to regulate blood sugar. Poor sleep stresses the body. This means your body produces more cortisol, a stress hormone. Cortisol makes it harder for the sugar-regulating hormone insulin to do its job, which means your blood sugar levels can rise. Even if your diet doesn’t change, sleep deprivation can push your blood glucose up. Your body becomes less sensitive to insulin, and your liver might release more glucose into the bloodstream thinking you’re in stress mode.

But isn’t black coffee good for diabetes?

Only in moderation. One or two cups a day usually don’t cause problems. But having five or six cups can backfire, especially when you’re not sleeping enough. High caffeine intake increases adrenaline and cortisol levels, just like lack of sleep does. Together, they create a double impact on your glucose control. So, caffeine indirectly raises your blood sugar, too.

Plus, excessive caffeine can lead to poor sleep quality — even if you do manage to get to bed on time. It becomes a cycle: less sleep, more coffee, more stress hormones, and higher blood sugar.

Studies suggest that in some people, especially those with prediabetes or type 2 diabetes, high caffeine consumption can reduce insulin sensitivity. This means that their bodies require more insulin to bring blood sugar levels down after meals, putting extra strain on the pancreas and increasing the risk of hyperglycemia.

Sleep is essential for glucose metabolism. And caffeine, though helpful in small doses, should be limited—especially if you’re using it to compensate for inadequate rest.

The ideal combination

Start by aiming for at least seven to eight hours of sleep per night. Try reducing your caffeine to two cups a day — preferably before 2 pm. Then monitor your blood sugar. You’ll likely see improvement within a week or two. These small lifestyle changes can go a long way in protecting your health — especially if you’re at a risk for diabetes or already managing it.

 

Saturday, 17 May 2025

What’s spiking BP in women in their early 30s and 40s faster than men?

 Source: https://indianexpress.com/article/health-wellness

Women between 30s and 40s often begin transitioning through perimenopause, a phase marked by fluctuating and gradually declining estrogen levels. (Representational)

Lately, I have been seeing a lot of women in their 30s and 40s with complaints of hypertension or high blood pressure. And I noticed that most of them lived in some of Mumbai’s most polluted areas. While the impact of pollution is generally associated with respiratory health, in women it can impact their biology and hormones.

Pollution and Blood Pressure

Research indicates that women may experience more pronounced cardiovascular responses to air pollution than men. Exposure to pollutants like fine particulate matter (PM2.5) and nitrogen dioxide (NO) has been linked to steeper blood pressure spikes in women. This is because of two reasons. One, women typically have smaller airways, which may allow pollutants to exert a greater physiological impact and obstruct them further. Second, their hormonal cycles and stress levels heighten their sensitivity to environmental triggers.

Hormonal Shifts and Cardiovascular Risk

Women between 30s and 40s often begin transitioning through perimenopause, a phase marked by fluctuating and gradually declining estrogen levels. Estrogen, known for its protective effects on the cardiovascular system, helps maintain blood vessel flexibility and suppresses inflammation. Pollutants like PM2.5 damage cells and trigger inflammation, which, in the absence of adequate estrogen, can damage walls of blood vessels—a precursor to chronic high blood pressure.

Pollutants of Concern

PM2.5 stands out as the most hazardous. These microscopic particles can penetrate deep into the lungs and even enter the bloodstream, igniting inflammation and damaging blood vessels. Nitrogen dioxide (NO) from vehicle exhaust leads to arterial stiffness. Carbon monoxide (CO) interferes with oxygen transport, forcing the heart to work harder, while ozone (O)—though less studied—has been shown to exacerbate cardiovascular and respiratory conditions. In urban areas, where traffic, construction, and industrial emissions converge, daily exposure to this toxic mix becomes unavoidable.

Many offices and homes suffer from poor ventilation, leading to constant exposure to indoor air pollutants as well. Combined with chronic stress, irregular routines, and limited physical activity, this creates a high-risk environment for cardiovascular problems.

Urban working women also often deal with long screen hours, shift work and low sun exposure — factors that further disrupt metabolic balance and vitamin D levels, both of which are closely linked to blood pressure regulation.

Taking Control: Prevention and Management

Since hypertension is a silent killer, women must do the following:

• Monitor regularly: Schedule routine check-ups for blood pressure, cholesterol and lipid profiles.

• Stay protected: Use indoor air purifiers and wear N95 masks when pollution levels are high.

• Eat smart: Adopt an anti-inflammatory diet rich in antioxidants, fibre and Omega-3 fatty acids.

• Move daily: Engage in regular physical activity, preferably indoors or in clean-air zones like parks.

• Manage stress: Practise mindfulness techniques such as yoga, breathing exercises, or meditation.

• Track the air: Use air quality index (AQI) apps and avoid outdoor activity during peak pollution hours.

 

Sunday, 4 May 2025

Doctors revive heart attack patients in remote TN pockets with a little help from WhatsApp: How a hub and spoke model works

 Source: https://indianexpress.com/article/health-wellness

A study conducted by the Institute of Cardiology at Madras Medical College connected 188 smaller hospitals, which do not have catheter labs for angioplasty procedures, to 18 big hospitals in Tamil Nadu as part of a “hub and spoke” therapy model.

What if a person suffers a heart attack in a remote village and the local health centre doesn’t have a cardiologist or the infrastructure to do an angioplasty — a procedure to remove blood clots from heart arteries? The patient can still live and recover if the centre is connected to a bigger hospital through a chat platform, where specialists can recommend clot-dissolving drugs to local healthcare personnel and buy some time for the patient to get to a bigger hospital for surgical interventions.

A study conducted by the Institute of Cardiology at Madras Medical College connected 188 smaller hospitals, which do not have catheter labs for angioplasty procedures, to 18 big hospitals in Tamil Nadu as part of a “hub and spoke” therapy model. Cardiologists at bigger hospitals read the ECG, patient history and test results, suggested drugs and procedures, all through WhatsApp, improving the odds of patients at smaller centres surviving a heart attack.

What a pilot study shows

The study, which covered 71,000 people over five years, was able to demonstrate that just by providing guidance to the smaller hospitals on WhatsApp, more lives could be saved. Within five years, nearly one in five patients treated for heart attack in the hub hospital came from a spoke hospital, indicating how the linking system improved access. In the second phase of the study done with six hub hospitals, the doctors saw a remarkable increase in the proportion of people who got any intervention from 52.6 per cent in 2019 to 87.1 per cent by 2022.

The findings, which were recently published in the Indian Journal of Medical Research, are significant because they lay the template for broad-basing cardiac care to cover the last mile. With more Indians experiencing heart attacks in their early years, such a public health intervention can make heart care accessible even during emergencies. The data is from the cardiac care policy implemented by the government of Tamil Nadu.

Why this model can reduce deaths from heart attacks

“The sooner a person can undergo a procedure to open up a heart blockage or at least get a medicine that can help in dissolving the clot, the more muscles we end up saving. Sadly, a very small proportion of people receive these timely interventions,” said Dr G Justin Paul, professor at the Madras Medical College who designed the model. He also leads the state government’s heart attack management programme team.

“There are two types of heart attacks. A STEMI (ST-elevation Myocardial Infarction) is a major heart attack where the clot blocks blood flow completely to a part of the heart, resulting in muscles dying. Non-STEMI is referred to as a minor heart attack. Once the heart muscles die, there is no way of reviving them. However, there is now enough evidence to show that giving the clot-dissolving drug immediately and then doing the procedure within 24 hours is also equally effective. While most hospitals may not be able to do the procedure, they can certainly give the drug and then move the patients to the bigger hub hospital,” said Dr Paul.

In fact, the WhatsApp chat platform also helps the smaller centres share transfer protocols and coordinate patient care with the bigger hospitals. “This system of care worked in Tamil Nadu because of the availability of cardiologists in several Government hospitals, even in those that did not have a catheter lab prior to the study. This may not be true for all of India. However, the model may be modified and adopted,” said Dr Paul.

Benefits in numbers

In the first cluster with 12 hub hospitals, including the key Madras Medical College, the proportion of patients undergoing the stenting procedure after getting the clot dissolving medicine streptokinase increased from 9.1 per cent to 33.2 per cent. The proportion of patients able to receive the procedure within hours of heart attack also increased from 5.7 per cent to 9.7 per cent.

“The cost of angioplasty in a private hospital — which can range from Rs 1.5 lakh to Rs 6 lakh — can be a deterrent. But, more importantly, not all hospitals have the facility to conduct the procedure. This is the reason many may not be able to get the procedure within a few hours of the heart attack,” reasoned Dr Paul.

The results from the second cluster were even more impressive. While the proportion of patients undergoing the procedure immediately remained the same, those getting the procedure after having received the medicine increased from 0.9 per cent to 5.3 per cent. The proportion of deaths also reduced from 8.5 per cent to 5.8 per cent.

While the study used the less costly streptokinase that is given as an infusion, newer drugs can also be used. “These one-shot injections are costly at present, but the price may be brought down by governmental action, much in the same way as the stent prices were lowered,” said Dr Paul.

 

Tuesday, 29 April 2025

An hour’s screen use in bed increases risk of insomnia by 59%: Why new study calls for sleep hygiene reset

 Source: https://indianexpress.com/article/health-wellness

Scientists have found another reason to put the phone down. A survey of 45,202 young adults in Norway has discovered that screen-scrolling in bed drives up your risk of insomnia by 59 per cent and cuts your sleep time by 24 minutes. However, social media was not more disruptive than other screen activities, according to a new study published in Frontiers of Psychiatry.

Insomnia is defined as trouble sleeping and daytime sleepiness at least three times a week over at least three months. While the study did not determine causality — for example whether screen use causes insomnia or if students with insomnia use screens more — researchers found that using a screen in bed at night makes it much more likely you will sleep less and sleep poorly.

All screen devices to blame: Laptop, mobile, TV and Kindle

Sleep problems are widespread and according to ENT surgeon and sleep disorder expert Dr Seemab Shaikh, even studies from AIIMS have shown that sleep disorders, particularly Obstructive Sleep Apnea, affect 34 per cent of the population, meaning one in three individuals. “Whether it’s a laptop, mobile, TV, or even a Kindle, these devices keep you awake and can distract you from falling asleep. The blue light emitted by these devices hits the retina and activates the cells connected to the brain’s centre, disrupting sleep. This delay in falling asleep leads to a delayed wake-up time, throwing off your entire circadian rhythm. This can lead to short-term memory loss, irritability, mood swings and daytime headaches,” said Dr Shaikh.

Why the type of screen doesn’t matter

Scientists used the 2022 Students’ Health and Wellbeing survey of 45,202 participants in full-time higher education aged between 18 and 28. They sorted responses into three categories, one where participants used social media, one where they did not mention social media and one where participants selected several activities, including social media. Researchers found increasing screen time after bedtime by one hour in any of these categories increased the odds of insomnia symptoms by 59 per cent and lowered sleep duration by 24 minutes. “Using a screen in bed at night makes it much more likely you will sleep less and sleep poorly, but social media use is no worse than any other form of screen time,” said the authors. There was no significant difference between social media and other screen activities, suggesting that screen use itself is the key factor in sleep disruption. This is likely due to time displacement where screen use delays sleep by taking up time that would otherwise be spent resting.

Top of Form

Bottom of Form

How to reduce screen use

Researchers suggested stopping screen use at least 30-60 minutes before sleep. “Consider disabling notifications to minimize disruptions during the night,” they said. Dr Shaikh suggests maintaining a sleep diary of consistent sleep schedules, a comfortable sleep environment and avoiding caffeine and alcohol at least six hours before.

 

Wednesday, 9 April 2025

An hour’s screen use in bed increases risk of insomnia by 59%: Why new study calls for sleep hygiene reset

 Source: https://indianexpress.com/article/health-wellness

Researchers suggested stopping screen use at least 30-60 minutes before sleep. (Photo: Pexels)

Scientists have found another reason to put the phone down. A survey of 45,202 young adults in Norway has discovered that screen-scrolling in bed drives up your risk of insomnia by 59 per cent and cuts your sleep time by 24 minutes. However, social media was not more disruptive than other screen activities, according to a new study published in Frontiers of Psychiatry.

Insomnia is defined as trouble sleeping and daytime sleepiness at least three times a week over at least three months. While the study did not determine causality — for example whether screen use causes insomnia or if students with insomnia use screens more — researchers found that using a screen in bed at night makes it much more likely you will sleep less and sleep poorly.

All screen devices to blame: Laptop, mobile, TV and Kindle

Sleep problems are widespread and according to ENT surgeon and sleep disorder expert Dr Seemab Shaikh, even studies from AIIMS have shown that sleep disorders, particularly Obstructive Sleep Apnea, affect 34 per cent of the population, meaning one in three individuals. “Whether it’s a laptop, mobile, TV, or even a Kindle, these devices keep you awake and can distract you from falling asleep. The blue light emitted by these devices hits the retina and activates the cells connected to the brain’s centre, disrupting sleep. This delay in falling asleep leads to a delayed wake-up time, throwing off your entire circadian rhythm. This can lead to short-term memory loss, irritability, mood swings and daytime headaches,” said Dr Shaikh.

Why the type of screen doesn’t matter

Scientists used the 2022 Students’ Health and Wellbeing survey of 45,202 participants in full-time higher education aged between 18 and 28. They sorted responses into three categories, one where participants used social media, one where they did not mention social media and one where participants selected several activities, including social media. Researchers found increasing screen time after bedtime by one hour in any of these categories increased the odds of insomnia symptoms by 59 per cent and lowered sleep duration by 24 minutes. “Using a screen in bed at night makes it much more likely you will sleep less and sleep poorly, but social media use is no worse than any other form of screen time,” said the authors. There was no significant difference between social media and other screen activities, suggesting that screen use itself is the key factor in sleep disruption. This is likely due to time displacement where screen use delays sleep by taking up time that would otherwise be spent resting.

How to reduce screen use

Researchers suggested stopping screen use at least 30-60 minutes before sleep. “Consider disabling notifications to minimize disruptions during the night,” they said. Dr Shaikh suggests maintaining a sleep diary of consistent sleep schedules, a comfortable sleep environment and avoiding caffeine and alcohol at least six hours before.