Written by Dr. Ambrish Mithal
Source: https://indianexpress.com/article/health-wellness
Over the past few months, social media has been
flooded by new information about the diagnosis of diabetes that runs contrary
to science. Many people believe in these fake unscientific forwards on their
phone and end up damaging their health.
What’s floating online?
Most of these so-called experts
claim the following:
1. The criteria for diagnosis of
diabetes has been altered frequently in recent years.
2. These alterations have reduced
the threshold level of blood sugar used to diagnose diabetes.
3. Reduction in diagnostic levels
leads to millions of additional people being labelled as diabetics.
4. These changes are decided upon
by a few ‘wise’ men seated on a table according to their whims, based on random
parameters.
5. More people being diagnosed
with diabetes means more will require medication.
6. All experts who are involved
in this decision making are hand-in-glove with drug manufacturers. So
ultimately the process is driven by the pharmaceutical industry so that they
can make billions of dollars.
Are these allegations true?
In 1979, the WHO formally defined diagnostic
criteria for diabetes mellitus based primarily on plasma glucose levels —
fasting plasma glucose more than or equal to 140 mg/dl, and a two-hour
post-glucose value more than 200 mg/dl.
In 1997, the threshold for fasting plasma glucose
was lowered to 126 mg/dl by the American Diabetes Association (ADA). The
post-glucose cut-off of 200 mg/dl was retained. The 1997 changes in the
diagnostic criteria for diabetes were influenced by studies which provided
evidence that levels between 126 and 140 mg/dl were also associated with an
increased risk of diabetes-related complications, supporting the need for lower
diagnostic thresholds for diabetes.
The diagnostic criteria for diabetes have not
changed since 1997.
What about prediabetes?
The 1979 WHO criteria recognised impaired glucose
tolerance as a post-glucose value between 140 and 199 mg/dl. This is the same
as we use today. The major change in 1997 was the inclusion of a category
called impaired fasting glucose — fasting glucose values between 110 and 125
mg/dl. In 2003, the ADA further lowered the fasting glucose criterion to 100
mg/dl. Some studies showed that individuals with fasting glucose levels between
100 and 109 mg/dL were also at a higher risk of progressing to Type 2 diabetes.
Additional research indicated that fasting glucose levels in the range of 100
to 109 mg/dL were associated with an increased risk of cardiovascular diseases.
However, the WHO continued to use a fasting level of 110 mg/dl as a cut-off.
Glucose Testing and
Interpretation
Since then the cut-offs for fasting plasma glucose
and oral glucose tolerance tests have remained the same with the only change
being HbA1c (average blood sugar counts of three months) included in 2009. An
HbA1c level of 6.5 per cent or more is diagnostic of diabetes mellitus. Levels
between 5.7 to 6.4 per cent indicate prediabetes.
The importance of prediabetes lies in the risk of
its conversion to diabetes or possible remission. In India 60 per cent of those
with prediabetes convert to diabetes in five years. Initiatives like the Indian
Diabetes Prevention Programme (IDPP) have demonstrated that lifestyle
interventions can reduce the risk of progression to diabetes by about 28-35 per
cent. Medications are used for a minuscule number of people with prediabetes.
The last change in diagnostic criteria in 2003 added a large number of people
to the pool of prediabetes so that people could recognise their risk and
initiate lifestyle changes.
The increase in diabetes prevalence is real and not
because of changed criteria. Consult a qualified practitioner.
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