Electric field-based dressing fights bacterial
infections
Amid growing antibiotic resistance, Indian-origin researchers
have developed a way to charge up the fight against bacterial infections using electricity. The
electric field-based dressing can not only disrupt biofilm infection, it can
also prevent such infections from forming in the future, said the study
published in the journal Annals of Surgery. Bacterial biofilms are thin, slimy
films of bacteria that form on some wounds, including burns or post-surgical infections, as well as
after a medical device is placed in the body.
These bacteria generate their own electricity, using
their own electric fields to communicate and form the biofilm, which makes
them more hostile and difficult to treat. The dressing electrochemically
self-generates 1 volt of electricity upon contact with body fluids such as
wound fluid or blood, which is not enough to hurt or electrocute the patient,
said the study. Work conducted at the Indiana University School of Medicine by
Chandan Sen and and Sashwati Roy led to the development of the dressing,
Indiana University said in a statement on Friday.
They discovered the dressing is not only successful in
fighting the bacteria on its own, but when combined with other medications can
make them even more effective. The researchers believe that the discovery has
the potential to create significant changes in the way physicians treat
patients with bacterial infections which are resistant to antibiotics. “This
shows for the first time that bacterial biofilm can be disrupted by using an
electroceutical dressing,” said Chandan Sen, Director of the Indiana Center for
Regenerative Medicine and Engineering.
“This has implications across surgery as biofilm
presence can lead to many complications in successful surgical outcomes,” Sen
added.
20.05.2019
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