Migraines more common among
females – Know why
A new research has found that women are more prone to migraines and other
stress-related disorders. This is because of of distinct differences found in
mast cells, a type of white blood cell that is part of the immune system, says
a study.
Mast cells are an important category of immune cells because they play
a key role in stress-related health issues that are typically more common in
women such as allergic disorders, auto-immune diseases, migraines and irritable
bowel syndrome, or IBS.
"Over 8,000 differentially expressed genes were found in female
mast cells compared to male mast cells," said lead researcher Adam Moeser,
Associate Professor at Michigan State University in the US.
"While male and female mast cells have the same sets of genes on
their chromosomes, with the exception of the XY sex chromosomes, the way the
genes act vary immensely between the sexes," Moeser noted.
A further in-depth analysis of the genes within the RNA genome -- a
primary building block in all forms of life -- revealed an increase in activity
that is linked to the production and storage of inflammatory substances,
according to the study published in the journal Biology of Sex Differences.
These substances can create a more aggressive response in the body and
result in disease.
"This could explain why women, or men, are more or less vulnerable
to certain types of diseases," Moeser said.
With this new understanding of how different genes act, scientists
could eventually start developing new sex-specific treatments that target these
immune cells and stop the onset of disease, Moeser said.
09.02.2017
A negative state of mind never
brings a positive outcome
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