2016 Nobel Prize: Yoshinori Ohsumi
from Japan awarded the Nobel Prize in Medicine
Yoshinori Ohsumi is a Japanese cell biologist who
specialises in autophagy and is a professor in Tokyo Institute of Technology ‘s
Frontier Research Center. Today, Ohsumi has been awarded the 2016 Nobel Prize
in Physiology or Medicine for his discoveries of mechanisms for
autophagy(Autophagy is an intracellular degradation system that delivers
cytoplasmic constituents to the lysosome. Despite its simplicity, recent
progress has demonstrated that autophagy plays a wide variety of physiological
and pathophysiological roles, which are sometimes complex). Ohsumi, 71, of the
Tokyo Institute of Technology discovered the mechanisms that allow cells to
break down and recycle unwanted components.The concept was first studied
closely in the 1960s when cells were observed destroying their own contents by
enclosing the item in a form of sack and then transporting it to a recycling
unit known as the lysosome for destruction.The Nobel Assembly at Karolinska
Institutet decided to award the prize to Ohsumi as his discoveries led to a new
paradigm in the ‘understanding of how the cell recycles its content’. Here’s a
list of other awards he has received till date:
·
Fujihara
Award, Fujihara Foundation of Science (2005)
·
Japan Academy
Prize, Japan Academy (2006)
·
Asahi Prize, Asahi
Shimbun (2009)
·
Kyoto Prize for
Basic Science (2012)
·
Gairdner Foundation
International Award (2015)
·
International Prize
for Biology (2015)
·
Keio Medical
Science Prize (2015)
·
Wiley Prize in
Biomedical Sciences (2016)
·
Nobel Prize in
Physiology or Medicine (2016)
‘His discoveries opened the path to understanding
the fundamental importance of autophagy in many physiological processes, such
as in the adaptation to starvation or response to infection,’ a statement on
the official website of the Nobel Prize said. It said that mutations in
autophagy genes can cause disease, and the process is involved in several
conditions including cancer and neurological disease.The 2015 Nobel Prize in Medicine
was awarded for discoveries concerning novel therapies against river blindness,
lymphatic filariasis and malaria to William C. Campbell, Satoshi Omura and
Youyou Tu.
Source: www.thehealthsite.com
04.10.2016
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